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Validation of Baveno VII criteria for clinically significant portal hypertension by two-dimensional shear wave elastography  期刊论文  

  • 编号:
    920B2DAA6C20612373D3E9DE3EDE8D90
  • 作者:
    He, Ruiling#[1,2]Liu, Chuan#[3,13]Grgurevic, Ivica#[4,5]Guo, Ying#[6]Xu, Huixiong(徐辉雄)#[7]Liu, Jiacheng(刘嘉城)#[8]Liu, Yunfang[6];Wang, Xiaoyan[6];Shi, Hongmei[9];Madir, Anita[10];Podrug, Kristian[11];Zhu, Yuli(朱宇莉)[7]Hua, Yongli[6];Wang, Kun[6];Wen, Jing[6];Su, Meiqin[9];Zhang, Qun(张群)[12]Li, Jie(李婕)*[8]Qi, Xiaolong(祁小龙)*[2]
  • 语种:
    英文
  • 期刊:
    HEPATOLOGY INTERNATIONAL ISSN:1936-0533 2024 年 18 卷 3 期 (1020 - 1028) ; JUN
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  • 摘要:

    Background The Baveno VII consensus proposed criteria for the non-invasively diagnosis of clinically significant portal hypertension (CSPH) in patients with compensated advanced chronic liver disease (cACLD). The performance of Baveno VII criteria for assessing CSPH by two-dimensional shear wave elastography (2D-SWE) had not been well validated. We aimed to validate the performance of Baveno VII criteria for rule-in and rule-out CSPH by 2D-SWE. Method This is an international multicenter study including cACLD patients from China and Croatia with paired liver stiffness measurement (LSM), spleen stiffness measurement (SSM) by 2D-SWE, and hepatic venous pressure gradient (HVPG) were included. CSPH was defined as HVPG >= 10 mmHg. Result A total of 146 patients with cACLD were enrolled, and finally 118 patients were included in the analysis. Among them, CSPH was documented in 79 (66.9%) patients. Applying the Baveno VII criteria for rule-out CSPH by 2D-SWE, [LSM <= 15 kPa and platelet count >= 150 x 109/L] OR SSM < 21 kPa, could exclude CSPH with sensitivity > 90% (93.5 or 98.7%) but negative predictive value < 90% (74.1 or 85.7%). Using the Baveno VII criteria for rule-in CSPH by 2D-SWE, LSM >= 25 kPa OR SSM >= 50 kPa, could diagnose CSPH with 100% specificity and 100% positive predictive values. Conclusion Baveno VII criteria by 2D-SWE showed a good diagnostic performance for ruling in but not for ruling out CSPH, which might become an emerging non-invasive elastography tool to select the patients who needed non-selective beta blocker therapy.

  • 推荐引用方式
    GB/T 7714:
    He Ruiling,Liu Chuan,Grgurevic Ivica, et al. Validation of Baveno VII criteria for clinically significant portal hypertension by two-dimensional shear wave elastography [J].HEPATOLOGY INTERNATIONAL,2024,18(3):1020-1028.
  • APA:
    He Ruiling,Liu Chuan,Grgurevic Ivica,Guo Ying,&Qi Xiaolong.(2024).Validation of Baveno VII criteria for clinically significant portal hypertension by two-dimensional shear wave elastography .HEPATOLOGY INTERNATIONAL,18(3):1020-1028.
  • MLA:
    He Ruiling, et al. "Validation of Baveno VII criteria for clinically significant portal hypertension by two-dimensional shear wave elastography" .HEPATOLOGY INTERNATIONAL 18,3(2024):1020-1028.
  • 入库时间:
    6/2/2024 8:17:15 PM
  • 更新时间:
    6/2/2024 8:17:15 PM
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